Off, off and away… it’s gone. Sent it out Saturday November 5, 2016.
Monday here! Let’s check out the site before I learn all about me.
What’s even more interesting to me than the actual “Where are you from?” section of the results is actually… everything else. Like I mentioned in part 1– I am very, very sure my family is from Vietnam. But this DNA test is going to tell me more than just “You’re Asian.” Let’s have some fun and make some predictions of our own. Well, I’ll make the predictions– you may not know me as well as I know myself.
Part 1: Ancestry Predictions
After watching plenty of YouTube videos of 23andMe results, I know this part is just what country did you eventually come from thousands of years ago. Hundreds of years ago, I know “I” came from Central Vietnam on my father’s side– from Huế, Vietnam. Huế is the ancient royal capital of Vietnam, and the ancient seat of the Nguyen dynasty. Interestingly enough, my family was around back then (source: written records), but our last name never changed to Nguyen. (Quick Fact: There are so many Nguyen’s because of The Nguyen Dynasty, the king made everyone in the kingdom change their family name to Nguyen). How my family got away with it– no idea. I can deduce that part of my family was educated and non-working class because I have written records. Up until recent history, the literacy level of Vietnam was pretty low.
My paternal grandmother came from a farm in Huế, and did not read or write, until learning to do so after moving to The United States around the age of 60. My paternal grandfather fluently spoke at least 4 languages, including Vietnamese, English, French and Mandarin Chinese.
My maternal grandparents, I can predict the same thing. Further back, they were farmers in North Vietnam before the country split in two. After the country split, my maternal grandfather worked for The Department of Agriculture for the South Vietnamese government. From this, I gather, the family was also educated for my grandfather to have also been literate.
23 and Me Haplogroup Map example
“In human genetics, the haplogroups most commonly studied are Y-chromosome (Y-DNA) haplogroups and mitochondrial DNA (DNA) haplogroups, both of which can be used to define genetic populations. Y-DNA is passed solely along the paternal line, from father to son, while DNA is passed down the maternal line, from mother to offspring of both sexes. Neither recombines, and thus Y-DNA and DNA change only by chance mutation at each generation with no intermixture between parents’ genetic material.”
I am not a man. (Surprise! Surprise!) I do not have a y-chromosome. So, I don’t know what will pop up here when the results finally come in, but it may be similar to the map above. “The haplogroup map shows you where most of the people with a given haplogroup lived prior to the age of European exploration, about 500 years ago. Before that time people moved a little less, and rarely moved between continents. Therefore the map reveals where people with a particular haplogroup lived for thousands of years.”
I am pretty sure we all come from neanderthals. The only thing this part of the test is going to tell me is just how much of a neanderthal I am– or how evolved I am. This sounds like a lawsuit waiting to happen. Good thing they have disclaimers! My prediction: there’s gotta be some-percentage, right? I’d like to think I’m pretty evolved– so my prediction is… close to none, but there’s going to be something.
Part 2: Carrier Status
There is a whole list of diseases 23andMe will test for. I really can’t predict the entire list, but a few, I have a good idea of what the test might reveal for me.
Note: Not a biologist and I’m not going to do anymore research beyond Wikipedia for my predictions. If something in the results shows up that peak my interest, I MAY look more into it.
There are so many! So I’m just going to go ahead and predict 100% no for everything.
Agenesis of the Corpus Callosum with Peripheral Neuropathy
Autosomal Recessive Polycystic Kidney Disease
Beta Thalassemia and Related Hemoglobinopathies
Congenital Disorder of Glycosylation Type 1a (PMM2-CDG)
D-Bifunctional Protein Deficiency
Dihydrolipoamide Dehydrogenase Deficiency
Fanconi Anemia Group C
Glycogen Storage Disease Type Ia
Glycogen Storage Disease Type Ib
Hereditary Fructose Intolerance
Herlitz Junctional Epidermolysis Bullosa (LAMB3-Related)
Leigh Syndrome, French Canadian Type
Limb-Girdle Muscular Dystrophy Type 2D
Limb-Girdle Muscular Dystrophy Type 2E
Limb-Girdle Muscular Dystrophy Type 2I
Maple Syrup Urine Disease Type 1B
Mucolipidosis Type IV
Neuronal Ceroid Lipofuscinosis (CLN5-Related)
Neuronal Ceroid Lipofuscinosis (PPT1-Related)
Niemann-Pick Disease Type A
Nijmegen Breakage Syndrome
Nonsyndromic Hearing Loss and Deafness, DFNB1 (GJB2-Related)
Pendred Syndrome and DFNB4 Hearing Loss
Phenylketonuria and Related Disorders
Primary Hyperoxaluria Type 2
Rhizomelic Chondrodysplasia Punctata Type 1
Sickle Cell Anemia
Tyrosinemia Type I
Usher Syndrome Type 1F
Usher Syndrome Type 3A
Zellweger Syndrome Spectrum (PEX1-Related)
Part 3: Traits
Self-explanatory, right? What makes me unique?
The European site includes what may/may not show up on the tests… AND it has East Asian results! Well, I’m already disappointed!
Hair: I have straight hair, my sister has wavy, so… I’m thinking it was a 50/50 chance for me. Both parents have straight hair, but my maternal grandfather has wavy hair– or so I’ve been told. At 90, it’s mostly gone.
Physical Characteristics: Height- average? Asians are short, but I am 5’6″; that’s pretty tall for an Asian woman. My brother is 5’11”, so I’m thinking we’re an average height family. We are American-born growing up eating American food, with American hormones and American milk– so that probably has a huge factor on our height.
Physical Responses: This is a weird thing like sneezing if a smell is too rich, like chocolate or Vietnamese coffee. I don’t have that at all.
Skin: No freckles and I tan easily. My dad’s family has 0 zits and 0 acne as teenagers, adults, no matter what they do. My mom’s family has crazy zits and acne as teenagers and adults no matter what they do. As for me, I had a few zits as a teenager but haven’t had any since.
Taste and Smell: I can smell. I can taste bitter things.
Alcohol flush: I DEFINITELY have the Asian glow. Makeup usually does a good job of hiding that. Although my ears do turn red. I always say, “I’m not drunk! I swear! It’s the Asian me! My dad has it. My mom doesn’t drink at all– so I don’t know if she has it or not, but her brothers definitely have it. Not much surprise expected in this category.
Caffeine consumption: Personally, I drink a lot of coffee. A lot. When I first started out in accounting, I drank about 5 cups a day. Now, I have one cup a day, but extra, extra strong Vietnamese coffee. I predict no sensitivity. If I did have that, I’d probably be dead right now– either from a heart attack, or from being so hyped up I’m just running around and around in circles until I run in the street. Good news is, I have a lower risk of premature death according to this trait.
Deep sleep: I have pretty vivid dreams, but I’m tired when I wake up and have trouble falling asleep. This is a toss-up for me.
Lactose intolerance: I don’t have it. Don’t know anyone who does. This is not the same as a sensitivity to dairy which many adults develop later in life no matter their tolerance as kids. This is why I can’t eat too much yogurt.
Muscle composition: Am I sprinter or a power muscle type? I’d say power muscle, because I hate running. I hate it, because my entire life, I have never been a good runner. I was an AWESOME swimmer (if I do say so myself), played well in all kind of sports, like basketball (which includes running)… but just running? Blegh.
Saturated fat and weight: I’m going to predict I am more likely to be at a lower weight, and have less saturated fat. I know this because I eat like poop and have stopped exercising like I used to. I’m not as firm, but I’m basically the same size I was when I was 14 years old– just an inch taller and a bit jigglier.
Sleep movement: Do I move when I sleep? No. At least according to my sleep partner and 2 different iPhone apps.
See you in 6-8 weeks!